Products
Adapalene
Adapalene is a third-generation topical retinoid primarily prescribed for the treatment of mild-to-moderate acne vulgaris. By binding to specific retinoic acid nuclear receptors, it modulates cellular differentiation, keratinization, and inflammatory processes. It effectively reduces comedone formation and exerts a potent anti-inflammatory action, making it a critical choice for dermatological gels and creams.
Develop Trusted Dermatology Drugs with Our Adapalene API
Product Specifications
| Adapalene API Technical Details | |
|---|---|
| Product Name | Adapalene |
| Category | API – Organic (Retinoid) |
| Chemical Name | 6-[3-(1-Adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid |
| CAS Number | 106685-40-9 |
| Molecular Formula | C₂₈H₂₈O₃ |
| Molecular Weight | 412.52 g/mol |
| Pharmacopoeia Compliance | USP / EP / BP |
| Therapeutic Category / Application | Topical retinoid for acne vulgaris; also used off-label for photoaging and keratosis pilaris |
| Form | White to off-white crystalline powder |
| Packaging | HDPE drum |
| Shelf Life | 3-4 Years |
| Storage Conditions | Store in tight containers at controlled room temperature, protected from direct light. |
| Certifications / Compliance | GMP, WHO-GMP, ISO 9001 |
For decades, Adapalene has been a cornerstone in dermatological therapy, especially for the management of acne vulgaris. As a third-generation topical retinoid, it normalizes follicular keratinization, reduces microcomedone formation, and exhibits anti-inflammatory activity, making it a preferred choice for both prescription and OTC acne regimens.
As a leading Adapalene API manufacturer in India, SNA Healthcare supplies high-purity Adapalene to formulation companies developing gels, creams, lotions, and combination products (e.g., with clindamycin or benzoyl peroxide). Our focus on consistency, low impurity profiles, and pharmacopoeial compliance ensures reliable performance in sensitive topical dermatology products.
Application of Adapalene API in Dermatology Formulations
Acne Therapy
Adapalene is a first-line topical retinoid for mild to moderate acne vulgaris. It acts on retinoic acid receptors to unclog pores, reduce comedones, and calm inflammation, with a favorable tolerability profile compared to earlier retinoids.
Combination & Specialty Products
Beyond monotherapy, Adapalene API is widely used in fixed-dose combinations (e.g., Adapalene + Benzoyl Peroxide, Adapalene + Clindamycin) and in formulations targeting post-acne marks, keratosis pilaris, and photoaging. Its chemical stability and compatibility support diverse semi-solid and liquid dosage forms.
Purity in All Applications
Whether formulated as a 0.1% or 0.3% gel, cream, or lotion, the purity and particle characteristics of Adapalene API critically influence efficacy and skin tolerability. Our material is manufactured to meet USP/EP/BP/IP standards with tight control on related substances and residuals.
Trust Factor
Batch-to-batch consistency in physical properties (assay, particle size, moisture) ensures predictable processing during gel/cream manufacturing and consistent clinical performance. This reliability is essential for both domestic and export-oriented dermatology brands.
Time to Buy Adapalene API!
When selecting high-grade Adapalene API, partnering with an experienced, pharmacopoeia-compliant manufacturer is critical. As a trusted Adapalene supplier in India, we provide API that meets global quality expectations for topical dermatology formulations. Contact us to secure a reliable supply of Adapalene API for your acne and skincare product portfolio.
PRODUCT IDENTIFICATION
CAS NO. : 1134-47-0
EINECS NO. : 214-486-9
Formula : C10H12C1NO2
PHYSICAL AND CHEMICAL PROPERTIES
Physical State: White crystalline powder/crystals
Melting Point: NA
Stability: Stable under ordinary conditions
SALES SPECIFICATION
THERAPEUTIC CATEGORY
Skeletal Muscle Relaxant, Centrally Acting.
