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Phenibut Hydrochloride
Phenibut Hydrochloride is a phenylated derivative of the inhibitory neurotransmitter GABA. The addition of the phenyl ring allows it to easily cross the blood-brain barrier. It acts primarily as a GABA-B agonist and, at higher doses, a GABA-A agonist. It is used as a nootropic and anxiolytic agent, effective in reducing anxiety, improving sleep architectures, and enhancing cognitive focus.
Get Top-Quality Phenibut Hydrochloride Pharmaceutical Ingredient in India
Product Specifications
| Phenibut Hydrochloride API Technical Details | |
|---|---|
| Product Name | Phenibut Hydrochloride |
| Category | Active Pharmaceutical Ingredient / Intermediate (Research Grade) |
| Chemical Name | 4-Amino-3-phenylbutanoic acid hydrochloride (β-Phenyl-GABA HCl) |
| CAS Number | 3060-41-1 |
| Molecular Formula | C₁₀H₁₃NO₂·HCl |
| Molecular Weight | 215.68 g/mol (hydrochloride salt) |
| Pharmacopoeia Compliance | In‑house specification / QC validated |
| Therapeutic / Application | Anxiolytic and nootropic agent, GABAB agonist, used in research and development of neuropsychotropic formulations |
| Form | White to off‑white crystalline powder |
| Packaging | HDPE container / fibre drum with inner liner |
| Shelf Life | 24 months from date of manufacture (when stored as recommended) |
| Storage Conditions | Store below 25–30 °C, in a dry place, protected from light and moisture; keep container tightly closed |
| Solubility | Freely soluble in water, DMF and DMSO; slightly soluble in ethanol; practically insoluble in non‑polar solvents |
| Certifications / Compliance | In‑house QC tested, COA supplied with each batch; manufactured under controlled environment and documented GMP‑aligned practices |
Phenibut Hydrochloride (β‑phenyl‑γ‑aminobutyric acid HCl) is a synthetic analogue of the inhibitory neurotransmitter GABA, engineered to cross the blood–brain barrier more effectively through the addition of a phenyl group. In pharmaceutical and research environments, it serves as a neuropsychotropic agent with anxiolytic and cognition‑enhancing properties, making it a valuable component in advanced CNS‑focused development projects.
As a focused API and intermediate supplier in India, SNA Healthcare provides Phenibut Hydrochloride with stringent quality control, ensuring consistent purity, assay, and impurity profile. Our product is designed for manufacturers, formulators, and research organisations who require reliable neuroactive starting materials for the design and optimisation of new dosage forms and experimental therapies.
Phenibut Hydrochloride Role in Advanced CNS Research
Neuropsychotropic and Anxiolytic Development
Phenibut Hydrochloride acts primarily as a GABAB receptor agonist with additional dopaminergic modulation, providing a well‑characterised pharmacological profile for the development of anxiolytic and mood‑modulating formulations. Its structure allows medicinal chemists to study receptor binding, dose–response relationships, and CNS penetration characteristics.
Nootropic and Cognitive Function Studies
Due to its documented effects on attention, memory, and stress resilience, Phenibut Hydrochloride is frequently used as a reference compound in nootropic research. It enables comparative studies, structure–activity relationship (SAR) work, and formulation screening for next‑generation cognitive support products.
Model Compound in Neuroscience and Preclinical R&D
The molecule serves as a model gabapentinoid in preclinical investigations of GABAergic signalling, synaptic inhibition, and neuroprotective mechanisms. Its defined stereochemistry and receptor profile help in designing analogues with improved safety, pharmacokinetics, and therapeutic index.
Quality‑Sensitive Multi‑Step Synthesis
In complex CNS API synthesis and formulation development, the quality of Phenibut Hydrochloride directly impacts downstream performance and reproducibility. Our tight control on assay, residual solvents, heavy metals, and organic impurities ensures a robust starting point, reducing variability and supporting compliance with regulatory expectations in regulated markets.
Source Phenibut Hydrochloride with Confidence
For organisations involved in neuropsychotropic and nootropic research, the reliability of Phenibut Hydrochloride as an input material is critical. As a trusted Phenibut Hydrochloride pharmaceutical ingredient supplier in India, SNA Healthcare delivers consistent, QC‑validated batches suitable for advanced synthesis and formulation work. Contact us today to discuss your Phenibut Hydrochloride API and research‑grade requirements and to obtain detailed technical data and COA.
